Triethylenetetramine (trientine): a caloric restriction mimetic with a new mode of action

A novel caloric restriction mediator

Caloric restriction and immunosenescence: a current perspective.

The age-related decrease in immunologic function is believed to be the major predisposing factor contributing to increased morbidity and mortality with age. Hence, the restoration of immunologic function is expected to have a beneficial effect in reducing pathology and maintaining a healthy condition in advanced age. Among various intervention strategies, caloric restriction (CR) has been shown...

Inulin: A New Adjuvant With Unknown Mode of Action

Article history: Received 11 November 2016 Accepted 11 November 2016 Available online 15 November 2016 hepatitis B,West Nile virus, Japanese encephalitis, human immunodeficiency virus, SARS, and anthrax, amongst others. The carbohydrate was effective and safe in both experimental animals, as well as in humans. Yet, despite the large number of studies performed, its mechanism of action is still ...

solution of security constrained unit commitment problem by a new multi-objective optimization method

چکیده-پخش بار بهینه به عنوان یکی از ابزار زیر بنایی برای تحلیل سیستم های قدرت پیچیده ،برای مدت طولانی مورد بررسی قرار گرفته است.پخش بار بهینه توابع هدف یک سیستم قدرت از جمله تابع هزینه سوخت ،آلودگی ،تلفات را بهینه می کند،و هم زمان قیود سیستم قدرت را نیز برآورده می کند.در کلی ترین حالتopf یک مساله بهینه سازی غیر خطی ،غیر محدب،مقیاس بزرگ،و ایستا می باشد که می تواند شامل متغیرهای کنترلی پیوسته و گ...

Intermittent supplementation with rapamycin as a dietary restriction mimetic

is a complex process associated with accumulation of damage, loss of function and increased vulnerability to disease, leading ultimately to death. Despite the complicated etiology of aging, an important discovery of recent years has been that simple genetic alterations can cause a substantial increase in healthy lifespan in laboratory model organisms [1]. Many of these longevity-extending mutat...